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Journal Articles

A Multi-Chamber Pulsating-Flow Device with Optimized Spatial Shear Stress and Pressure for Endothelial-Cell Testing

Accepted Manuscript
Obed Campos, Antoni Garcia De Herreros, Antonio Sánchez, Jeffrey R. Fineman, Geno Pawlak
Journal: Journal of Biomechanical Engineering
Publisher: ASME
Article Type: Research-Article
J Biomech Eng.
Paper No: BIO-24-1158
https://doi.org/10.1115/1.4066800
Published Online: October 9, 2024
View Article titled, A Multi-Chamber Pulsating-Flow Device with Optimized Spatial Shear Stress and Pressure for Endothelial-Cell Testing
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Topics: Endothelial cells, Pressure, Pulsatile flow, Shear stress, Testing, Design, Flow (Dynamics), Fluctuations (Physics), Acoustics, Laplace equations
Journal Articles

Enhancing Inhalation Drug Delivery: A Comparative Study and Design Optimization of a Novel Valved Holding Chamber

Shahab Azimi, Siamak Arzanpour
Journal: Journal of Biomechanical Engineering
Publisher: ASME
Article Type: Research-Article
J Biomech Eng. April 2024, 146(4): 041002.
Paper No: BIO-23-1276
https://doi.org/10.1115/1.4064436
Published Online: February 7, 2024
View Article titled, Enhancing Inhalation Drug Delivery: A Comparative Study and Design Optimization of a Novel Valved Holding Chamber
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Topics: Design, Optimization, Particulate matter, Simulation, Valves, Drugs, Engineering prototypes, Flow (Dynamics), Drug delivery systems
Journal Articles

Fluid Flow Analysis of Neonatal Dual-Lumen Cannulas for Venovenous Extracorporeal Membrane Oxygenation

Danielle M. Sawka, Yunxing Su, Julie Monteagudo, Roberto Zenit
Journal: Journal of Biomechanical Engineering
Publisher: ASME
Article Type: Research-Article
J Biomech Eng. February 2024, 146(2): 021008.
Paper No: BIO-23-1237
https://doi.org/10.1115/1.4064212
Published Online: December 20, 2023
View Article titled, Fluid Flow Analysis of Neonatal Dual-Lumen Cannulas for Venovenous Extracorporeal Membrane Oxygenation
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Topics: Circuits, Flow (Dynamics), Fluid dynamics, Geometry, Membranes, Shear stress, Particulate matter, Blood, Variable structure systems, Transparency
Journal Articles

Evaluation of Soft Mist Inhaler Aerosol Velocity, Size, and Deposition Inside the Mouth—A Computational Fluid Dynamics Study

Taha Sadeghi, Leila Pakzad, Pedram Fatehi
Journal: Journal of Biomechanical Engineering
Publisher: ASME
Article Type: Research-Article
J Biomech Eng. June 2023, 145(6): 061007.
Paper No: BIO-22-1147
https://doi.org/10.1115/1.4056967
Published Online: March 8, 2023
View Article titled, Evaluation of Soft Mist Inhaler Aerosol Velocity, Size, and Deposition Inside the Mouth—A Computational Fluid Dynamics Study
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Topics: Aerosols, Computational fluid dynamics, Flow (Dynamics), Geometry, Nozzles, Particulate matter, Drugs
Journal Articles

Modeling the Mechanical Microenvironment of Coiled Cerebral Aneurysms

David I. Bass, Laurel M. M. Marsh, Patrick Fillingham, Do Lim, V. Keshav Chivukula, Louis J. Kim, Alberto Aliseda, Michael R. Levitt
Journal: Journal of Biomechanical Engineering
Publisher: ASME
Article Type: Research-Article
J Biomech Eng. April 2023, 145(4): 041005.
Paper No: BIO-22-1112
https://doi.org/10.1115/1.4055857
Published Online: December 5, 2022
View Article titled, Modeling the Mechanical Microenvironment of Coiled Cerebral Aneurysms
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Topics: Aneurysms, Particulate matter, Domes (Structural elements), Simulation, Modeling, Flow (Dynamics), Thrombosis, Porosity, Shear stress
Includes: Supplementary data
Journal Articles

Influence of the Anatomical Structure on the Hemodynamics of Iliac Vein Stenosis

Li Changsheng, Feng Haiquan, Wang Kun, Wang Xiaotian, Wang Yonggang
Journal: Journal of Biomechanical Engineering
Publisher: ASME
Article Type: Research-Article
J Biomech Eng. January 2023, 145(1): 011013.
Paper No: BIO-21-1445
https://doi.org/10.1115/1.4055307
Published Online: September 19, 2022
View Article titled, Influence of the Anatomical Structure on the Hemodynamics of Iliac Vein Stenosis
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Topics: Blood flow, Hemodynamics, Particulate matter, Shear stress, Vessels, Shear (Mechanics), Blood vessels, Flow (Dynamics), Computational fluid dynamics, Thrombosis
Journal Articles

Guiding the Prostatic Artery Embolization Procedure With Computational Fluid Dynamics

Mostafa Mahmoudi, Chadrick Jennings, Keith Pereira, Andrew F. Hall, Amirhossein Arzani
Journal: Journal of Biomechanical Engineering
Publisher: ASME
Article Type: Research-Article
J Biomech Eng. November 2022, 144(11): 111004.
Paper No: BIO-21-1381
https://doi.org/10.1115/1.4054515
Published Online: June 16, 2022
View Article titled, Guiding the Prostatic Artery Embolization Procedure With Computational Fluid Dynamics
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Topics: Aorta, Blood flow, Computational fluid dynamics, Hemodynamics, Particulate matter, Bifurcation, Flow (Dynamics)
Journal Articles

A Novel Device for the Quantification of Synovial Fluid Viscosity Via Magnetic Deflection

Samuel L. Armington, Yash Y. Shah, Jon Dobson, Kyle D. Allen
Journal: Journal of Biomechanical Engineering
Publisher: ASME
Article Type: Technical Briefs
J Biomech Eng. August 2022, 144(8): 084504.
Paper No: BIO-21-1357
https://doi.org/10.1115/1.4053794
Published Online: March 9, 2022
View Article titled, A Novel Device for the Quantification of Synovial Fluid Viscosity Via Magnetic Deflection
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Topics: Deflection, Flow (Dynamics), Fluids, Viscosity, Particulate matter, Experimental design
Journal Articles

Ramifications of Vorticity on Aggregation and Activation of Platelets in Bi-Leaflet Mechanical Heart Valve: Fluid–Structure-Interaction Study

Meraj Ahmed, Nirmal Gupta, Rashmoni Jana, Malay K. Das, Kamal K. Kar
Journal: Journal of Biomechanical Engineering
Publisher: ASME
Article Type: Research-Article
J Biomech Eng. August 2022, 144(8): 081002.
Paper No: BIO-21-1102
https://doi.org/10.1115/1.4053665
Published Online: February 21, 2022
View Article titled, Ramifications of Vorticity on Aggregation and Activation of Platelets in Bi-Leaflet Mechanical Heart Valve: Fluid–Structure-Interaction Study
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Topics: Flow (Dynamics), Fluids, Particulate matter, Platelets, Vorticity, Heart valve prostheses
Journal Articles

Development of Three-Stage Bioaerosol Sampler for Size-Selective Sampling

Jun-Hyung Lim, Sang Hwan Nam, Jongwoo Kim, Nam Hoon Kim, Gun-Soo Park, Jin-Soo Maeng, Se-Jin Yook
Journal: Journal of Biomechanical Engineering
Publisher: ASME
Article Type: Research-Article
J Biomech Eng. July 2022, 144(7): 071008.
Paper No: BIO-21-1249
https://doi.org/10.1115/1.4053504
Published Online: February 18, 2022
View Article titled, Development of Three-Stage Bioaerosol Sampler for Size-Selective Sampling
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Topics: Aerosols, Flow (Dynamics), Particulate matter, Fluids
Journal Articles

Stability of the Interface Between Two Immiscible Liquids in a Model Eye Subject to Saccadic Motion

Ru Wang, Jheng-Han Tsai, Martin P. Snead, Philip Alexander, D. Ian Wilson
Journal: Journal of Biomechanical Engineering
Publisher: ASME
Article Type: Research-Article
J Biomech Eng. May 2022, 144(5): 051004.
Paper No: BIO-20-1459
https://doi.org/10.1115/1.4053004
Published Online: December 20, 2021
View Article titled, Stability of the Interface Between Two Immiscible Liquids in a Model Eye Subject to Saccadic Motion
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Topics: Computational fluid dynamics, Flow (Dynamics), Fluids, Silicones, Simulation, Stability, Surface tension, Surfactants, Viscosity, Shapes
Includes: Supplementary data
Journal Articles

Review of the Development of Hemodynamic Modeling Techniques to Capture Flow Behavior in Arteries Affected by Aneurysm, Atherosclerosis, and Stenting

Petra N. Williamson, Paul D. Docherty, Sina G. Yazdi, Adib Khanafer, Natalia Kabaliuk, Mark Jermy, Patrick H. Geoghegan
Journal: Journal of Biomechanical Engineering
Publisher: ASME
Article Type: Research-Article
J Biomech Eng. April 2022, 144(4): 040802.
Paper No: BIO-20-1203
https://doi.org/10.1115/1.4053082
Published Online: December 17, 2021
View Article titled, Review of the Development of Hemodynamic Modeling Techniques to Capture Flow Behavior in Arteries Affected by Aneurysm, Atherosclerosis, and Stenting
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Topics: Computational fluid dynamics, Flow (Dynamics), Hemodynamics, Modeling, Particulate matter, Stents, Aneurysms, Boundary-value problems, Atherosclerosis, Fluids
Journal Articles

A First Assessment of an Aerodynamic Barrier Layer for Filtering Airborne Hygroscopic Particles

Francisco J. Arias, Salvador De Las Heras
Journal: Journal of Biomechanical Engineering
Publisher: ASME
Article Type: Research-Article
J Biomech Eng. February 2022, 144(2): 021006.
Paper No: BIO-21-1121
https://doi.org/10.1115/1.4052291
Published Online: September 23, 2021
View Article titled, A First Assessment of an Aerodynamic Barrier Layer for Filtering Airborne Hygroscopic Particles
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Topics: Drops, Filtration, Particulate matter, Fibers
Journal Articles

Improving Pulmonary Nanotherapeutics Using Helical Aerosol Streams: An In Silico Study

Adithya Gurumurthy, Clement Kleinstreuer
Journal: Journal of Biomechanical Engineering
Publisher: ASME
Article Type: Research-Article
J Biomech Eng. November 2021, 143(11): 111001.
Paper No: BIO-21-1035
https://doi.org/10.1115/1.4051217
Published Online: July 14, 2021
View Article titled, Improving Pulmonary Nanotherapeutics Using Helical Aerosol Streams: An In Silico Study
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Topics: Aerosols, Drugs, Flow (Dynamics), Nanoparticles, Particulate matter, Lung, Diffusion (Physics), Fluids, Drug delivery systems
Journal Articles

Computational Fluid Dynamics Study of Cerebral Thromboembolism Risk in Ventricular Assist Device Patients: Effects of Pulsatility and Thrombus Origin

Ray Prather, Eduardo Divo, Alain Kassab, William DeCampli
Journal: Journal of Biomechanical Engineering
Publisher: ASME
Article Type: Research-Article
J Biomech Eng. September 2021, 143(9): 091001.
Paper No: BIO-20-1332
https://doi.org/10.1115/1.4050819
Published Online: May 6, 2021
View Article titled, Computational Fluid Dynamics Study of Cerebral Thromboembolism Risk in Ventricular Assist Device Patients: Effects of Pulsatility and Thrombus Origin
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Topics: Computational fluid dynamics, Flow (Dynamics), Particulate matter, Thrombosis, Risk, Unsteady flow, Ventricular assist devices
Includes: Supplementary data
Journal Articles

Impact-Induced Cortical Strain Concentrations at the Sulcal Base and Its Implications for Mild Traumatic Brain Injury

Ashley Mazurkiewicz, Sheng Xu, Hanspeter Frei, Rohan Banton, Thuvan Piehler, Oren E. Petel
Journal: Journal of Biomechanical Engineering
Publisher: ASME
Article Type: Research-Article
J Biomech Eng. June 2021, 143(6): 061015.
Paper No: BIO-20-1330
https://doi.org/10.1115/1.4050283
Published Online: March 24, 2021
View Article titled, Impact-Induced Cortical Strain Concentrations at the Sulcal Base and Its Implications for Mild Traumatic Brain Injury
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Topics: Biological tissues, Brain, Particulate matter, Traumatic brain injury, Wounds, Shear (Mechanics)
Journal Articles

Visualizing the Flow Patterns in an Expanding and Contracting Pulmonary Alveolated Duct Based on Microcomputed Tomography Images

Toshihiro Sera, Naoki Kamiya, Taichi Fukushima, Gaku Tanaka
Journal: Journal of Biomechanical Engineering
Publisher: ASME
Article Type: Technical Briefs
J Biomech Eng. July 2021, 143(7): 074501.
Paper No: BIO-20-1457
https://doi.org/10.1115/1.4050285
Published Online: March 24, 2021
View Article titled, Visualizing the Flow Patterns in an Expanding and Contracting Pulmonary Alveolated Duct Based on Microcomputed Tomography Images
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Topics: Ducts, Flow (Dynamics), Particulate matter, Deformation, Radial flow
Journal Articles

Time-Resolved Echo-Particle Image/Tracking Velocimetry Measurement of Interactions Between Native Cardiac Output and Veno-Arterial ECMO Flows

Zeng Zhang, Xun Zhou, Alejandro Suarez-Pierre, Cecillia Lui, Sean Kearney, Enoch Yeung, Henry Halperin, Chun Woo Choi, Joseph Katz
Journal: Journal of Biomechanical Engineering
Publisher: ASME
Article Type: Research-Article
J Biomech Eng. February 2021, 143(2): 021008.
Paper No: BIO-20-1256
https://doi.org/10.1115/1.4048424
Published Online: October 30, 2020
View Article titled, Time-Resolved Echo-Particle Image/Tracking Velocimetry Measurement of Interactions Between Native Cardiac Output and Veno-Arterial ECMO Flows
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Topics: Bubbles, Echoes, Flow (Dynamics), Valves, Particulate matter, Ultrasound
Journal Articles

Lymphatic Valves Separate Lymph Flow Into a Central Stream and a Slow-Moving Peri-Valvular Milieu

Akshay Pujari, Alexander F. Smith, Joshua D. Hall, Patrick Mei, Kin Chau, Duy T. Nguyen, Daniel T. Sweet, Juan M. Jiménez
Journal: Journal of Biomechanical Engineering
Publisher: ASME
Article Type: Research-Article
J Biomech Eng. October 2020, 142(10): 100805.
Paper No: BIO-20-1021
https://doi.org/10.1115/1.4048028
Published Online: August 31, 2020
View Article titled, Lymphatic Valves Separate Lymph Flow Into a Central Stream and a Slow-Moving Peri-Valvular Milieu
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Topics: Flow (Dynamics), Valves, Vessels, Particulate matter
Journal Articles

Acoustic Cell Separation Based on Density and Mechanical Properties

Yuliang Xie, Zhangming Mao, Hunter Bachman, Peng Li, Peiran Zhang, Liqiang Ren, Mengxi Wu, Tony Jun Huang
Journal: Journal of Biomechanical Engineering
Publisher: ASME
Article Type: Research-Article
J Biomech Eng. March 2020, 142(3): 031005.
Paper No: BIO-19-1496
https://doi.org/10.1115/1.4046180
Published Online: February 28, 2020
View Article titled, Acoustic Cell Separation Based on Density and Mechanical Properties
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Topics: Acoustics, Density, Mechanical properties, Particulate matter, Separation (Technology), Pressure
Includes: Supplementary data