A computational model incorporating physiological motion and uniform transient wall deformation of a branchless right coronary artery (RCA) was developed to assess the influence of artery compliance on wall shear stress (WSS). Arterial geometry and deformation were derived from modern medical imaging techniques, whereas the blood flow was solved numerically employing a moving-grid approach using a well-validated in-house finite element code. The simulation results indicate that artery compliance affects the WSS in the RCA heterogeneously, with the distal region mostly experiencing these effects. Under physiological inflow conditions, coronary compliance contributed to phase changes in the WSS time history, without affecting the temporal gradient of the local WSS nor the bounds of the WSS magnitude. Compliance does not cause considerable changes to the topology of WSS vector patterns nor to the localization of WSS minima along the RCA. We conclude that compliance is not an important factor affecting local hemodynamics in the proximal region of the RCA while the influence of compliance in the distal region needs to be evaluated in conjunction with the outflow to the myocardium through the major branches of the RCA.
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e-mail: dimos.poulikakos@ethz.ch
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August 2008
Research Papers
A Study on the Compliance of a Right Coronary Artery and Its Impact on Wall Shear Stress
Dehong Zeng,
Dehong Zeng
Laboratory of Thermodynamics in Emerging Technologies, Department of Mechanical and Process Engineering,
ETH Zurich
, ML J 36, CH-8092 Zurich, Switzerland
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Evangelos Boutsianis,
Evangelos Boutsianis
Laboratory of Thermodynamics in Emerging Technologies, Department of Mechanical and Process Engineering,
ETH Zurich
, ML J 36, CH-8092 Zurich, Switzerland
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Marc Ammann,
Marc Ammann
Laboratory of Thermodynamics in Emerging Technologies, Department of Mechanical and Process Engineering,
ETH Zurich
, ML J 36, CH-8092 Zurich, Switzerland
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Kevin Boomsma,
Kevin Boomsma
Laboratory of Thermodynamics in Emerging Technologies, Department of Mechanical and Process Engineering,
ETH Zurich
, ML J 36, CH-8092 Zurich, Switzerland
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Simon Wildermuth,
Simon Wildermuth
Institute of Diagnostic Radiology,
University Hospital Zurich
, CH-8092 Zurich, Switzerland
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Dimos Poulikakos
Dimos Poulikakos
Laboratory of Thermodynamics in Emerging Technologies, Department of Mechanical and Process Engineering,
e-mail: dimos.poulikakos@ethz.ch
ETH Zurich
, ML J 36, CH-8092 Zurich, Switzerland
Search for other works by this author on:
Dehong Zeng
Laboratory of Thermodynamics in Emerging Technologies, Department of Mechanical and Process Engineering,
ETH Zurich
, ML J 36, CH-8092 Zurich, Switzerland
Evangelos Boutsianis
Laboratory of Thermodynamics in Emerging Technologies, Department of Mechanical and Process Engineering,
ETH Zurich
, ML J 36, CH-8092 Zurich, Switzerland
Marc Ammann
Laboratory of Thermodynamics in Emerging Technologies, Department of Mechanical and Process Engineering,
ETH Zurich
, ML J 36, CH-8092 Zurich, Switzerland
Kevin Boomsma
Laboratory of Thermodynamics in Emerging Technologies, Department of Mechanical and Process Engineering,
ETH Zurich
, ML J 36, CH-8092 Zurich, Switzerland
Simon Wildermuth
Institute of Diagnostic Radiology,
University Hospital Zurich
, CH-8092 Zurich, Switzerland
Dimos Poulikakos
Laboratory of Thermodynamics in Emerging Technologies, Department of Mechanical and Process Engineering,
ETH Zurich
, ML J 36, CH-8092 Zurich, Switzerlande-mail: dimos.poulikakos@ethz.ch
J Biomech Eng. Aug 2008, 130(4): 041014 (11 pages)
Published Online: June 11, 2008
Article history
Received:
May 14, 2007
Revised:
January 22, 2008
Published:
June 11, 2008
Citation
Zeng, D., Boutsianis, E., Ammann, M., Boomsma, K., Wildermuth, S., and Poulikakos, D. (June 11, 2008). "A Study on the Compliance of a Right Coronary Artery and Its Impact on Wall Shear Stress." ASME. J Biomech Eng. August 2008; 130(4): 041014. https://doi.org/10.1115/1.2937744
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