Planar function generating mechanisms may be synthesized for a limited number of precision points by carrying out a kinematic inversion about the output link. However, this becomes quite difficult for spatial mechanisms. In this paper the general RSSR spatial function generating mechanism is synthesized using the Selective Precision Synthesis technique. In this computer-aided design method, nonlinear constraint equations relating the generated and desired rotations of the output crank are formulated. These constraints which define accuracy neighborhoods around each of the “n” prescribed output crank rotations, are then solved using the Generalized Reduced Gradient Method of optimization. The mathematical formulation, the general procedure of synthesis and numerical examples are presented in this paper.