Deformation Compensation during Buoyancy-Enabled Inkjet Printing of 3D Soft Tubular Structures

[+] Author and Article Information
Kyle Christensen

Department of Mechanical and Aerospace Engineering, University of Florida, Gainesville, FL 32611, USA

Zhengyi Zhang

School of Naval Architecture and Ocean Engineering, Huazhong University of Science and Technology, Wuhan 430074, PR China

Changxue Xu

Department of Industrial, Manufacturing, and Systems Engineering, Texas Tech University, Lubbock, TX 79409, USA

Yong Huang

Department of Biomedical Engineering, University of Florida, Gainesville, FL 32611, USA; Department of Mechanical and Aerospace Engineering, University of Florida, Gainesville, FL 32611, USA

1Corresponding author.

ASME doi:10.1115/1.4037996 History: Received December 28, 2016; Revised August 31, 2017


Of various tissues being fabricated using bioprinting, three-dimensional (3D) soft tubular structures have often been the focus since they address the need for printable vasculature throughout a thick tissue and offer potential as perfusable platforms for biological studies. Drop-on-demand inkjetting has been favored as an effective technique to print such 3D soft tubular structures from various hydrogel bioinks. During the buoyancy-enabled inkjet fabrication of hydrogel-based soft tubular structures, they remain submerged in a solution which crosslinks the printed structures and provides a supporting buoyant force. However, because of the low stiffness of the structures, the structural deformation of printed tubes poses a significant challenge to the process effectiveness and efficiency. To overcome this structural deformation during buoyancy-enabled inkjet printing, predictive compensation approaches are developed to incorporate deformation allowance into the designed shape. Circumferential deformation is addressed by a four-zone approach which includes base, circular, vertical, and spanning zones for the determination of a designed cross section or compensated printing path. Axial deformation is addressed by the modification of the proposed circumferential compensation based on the distance of a given cross section to the junction of a branching tube. These approaches are found to enable the successful fabrication of straight and branching alginate tubular structures with nearly ideal geometry, providing a good foundation for the wide implementation of the buoyancy-enabled inkjetting technique. While inkjetting is studied here as a model bioprinting process, the resulting knowledge also applies to other buoyancy-enabled bioprinting techniques.

Copyright (c) 2017 by ASME
Your Session has timed out. Please sign back in to continue.






Some tools below are only available to our subscribers or users with an online account.

Related Content

Customize your page view by dragging and repositioning the boxes below.

Related Journal Articles
Related eBook Content
Topic Collections

Sorry! You do not have access to this content. For assistance or to subscribe, please contact us:

  • TELEPHONE: 1-800-843-2763 (Toll-free in the USA)
  • EMAIL: asmedigitalcollection@asme.org
Sign In